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RESEARCH

Overview of Current Projects
The Royal Society “Computational modelling of fibrinogen deposition in aortic dissection”. 2025-2026, IEC\NSFC\242269.

British Heart Foundation “Developing an integrated clinical imaging-based computational workflow for non-invasive risk stratification and assessment of hemodynamics in pulmonary hypertension.” 2025-2029. BHF Immediate Post-Doctoral Basic Science Research Fellowship to Dr Chloe Armour. FS/IPBSRF/24/ 27116.

British Heart Foundation “Development of a novel Aortic Dissection REpair Simulator System (ADRESS) to model clinical outcome prior to type A aortic dissection repair”, 2024-2028. BHF Immediate Post-Doctoral Basic Science Research Fellowship to Dr Yu Zhu. FS/IPBSRF/23/27098.

Heart Research UK “Predicting Thoracic Aortic Aneurysm progression with artificial intelligence to plan surveillance and elective surgery”, 2022-2025.

"Personalising computational models for analysis of aortic dissection haemodynamics". PhD student: Kaihong Wang.

"Multiscale computational modelling of thrombolytic therapies for the treatment of ischemic stroke". PhD student: Yilin Yang.

“Trabeculated left ventricular hemodynamics”. PhD student: Sihan Jiang.

"Hemodynamic and biomechanical modelling of thoracic endovascular procedures for complex aortic arch repair”. PhD student: Webster Li.

Selected past projects
“Fluid-structure interaction analysis of natural and bioprothetic aortic valves”. Researcher: Zhongjie Yin.
"Computational haemodynamic analysis of thoracic endovascular aortic repair for complex aortic arch diseases". Researcher: Sampad Sengupta.
“Mathematical modelling of nanoparticle transport through tumours for application in radiotherapy”. Researcher: George Caddy.
"Predicting stent induced new entry evolution in patient-specific Stanford B aortic dissection model". Researcher: Xiaoxin Kan.
"Analysis of haemodynamics and biomechanics of different aortic valve and root prostheses". Researcher: Emily Manchester.
"Predicting the Outcome of TEVAR for Type B Aortic Dissection". Researcher: Chloe Armour.
"Evaluate the hemodynamic performance of novel techniques and devices for endovascular repair of aortic aneurysms by using computational fluid dynamics". Researcher: Yu Zhu.
"Development of a multiphysics model for focused ultrasound-mediated drug delivery to brain tumour". Researcher: Yu Huang.
"Multi-scale modelling of drug delivery to solid tumors". Researcher: Moath Alamer.
"Patient-specific assessment of hemodynamic performance of surgical and transcatheter aortic valve replacements". Researcher: Selene Pirola.
"Mathematical modelling of thrombus formation in type B aortic dissection". Claudia Menichini.
"Thermosensitive nanoparticle mediated drug delivery for cancer and thrombolytic therapies". Researcher: Xin Zhang.
"Mathematical Modelling of Drug Delivery to Solid Tumour". Researcher: Wenbo Zhan.
"Effect of ageing on carotid artery morphology, hemodynamics, and the development of atherosclerosis". Researcher: Claudio Carallo.
"Analysis of carotid wall mechanics based on ultrasound imaging". Researcher: Zhongjie Wang.
"Development of computational methods for personalised assessment of the biomechanical functions of the Marfan aorta". Researcher: Shelly Singh.
"Analysis of morphology and flow in the aorta: comparison between bicuspid and tricuspid aortic valves". Researcher: Oluwatoyin Fatona.
"Analysis of haemodynamic forces in fenestrated stent grafts for abdominal aortic aneurysms" Researcher: Harkamaljot Kandail.
"Modelling of reverse osmosis membrane process and transport phenomena for performance analysis and optimisation". Researcher: Boram Gu.
"Investigation of geometric features and flap motion on the progression of aortic dissection". Researcher: Ana Crispin Corzo.
"Development of a multi-physics model for thermosensitive liposomal delivery of drugs activated by focused ultrasound". Researcher: Andris Piebalgs.