ProfessorVictoria Cornelius

Research funding

FUNDING AWARDS

2025-2028 Precision Antimicrobial Treatment in Hospitals for Sepsis Trial. The development of a data-enabled Sequential Multiple Assignment Randomised Trial (SMART) to guide precision antimicrobial prescribing in hospitalised patients (PATH). Professor Victoria Cornelius and Dr Timothy Rawson. Fleming Initiative. £7M

2025-2030 An efficient, UK-wide, real-world-data-enabled, group-sequential, randomised controlled trial to determine clinical efficacy, effect size, and safety of widely used enteral feeds in reducing necrotising enterocolitis, mortality, and cognitive impairment in extremely preterm babies (COLLABORATE). Professor Victoria Cornelius and Professor Neena Modi. NIHR EME. £3M

2024-2029 National Institute for Health and Care Research Research Support Service (NIHR RSS)-WP4 National Coordinating Centre: NIHR Research Methods Academy. (Infrastructure award). University of Birmingham. DHSC. £0.5M

2024-2029 Precision medicine Adaptive Network platform Trial in Hypoxemic acutE respiratory failuRe (PANTHER). Professor Danny McAuley. NIHR EME. £6M

2023-2028 National Institute for Health and Care Research Research Support Service Imperial College London and Partners Hub (NIHR RSS Infrastructure Award). Professor Victoria Cornelius and Professor Greta Rait. DHSC. £8.7M

2023-2027 A Multi-Site Randomised Controlled Trial to Evaluate the Impact of a Group Treatment For Antenatal Anxiety (ACORN II). Professor Heather O'Mahen. NIHR HTA. £1.8M

2023-2025 Improving newborn care through real-world-health-data-facilitated, digital-technology-supported randomised clinical trials (MICI). Professor Neena Modi. MRC. £0.6M

2022-2023 Building an international precision medicine platform trial for the acute respiratory distress syndrome (PANTHER). Professor Danny McAuley. NIHR EME Accelerator Award. £0.18M

2022-2023 Randomized embedded, mulifactorial, adaptive platform trial for interstitial lung disease (REMAP-ILD). Professor Gisli Jenkins. NIHR EME Accelerator Award. £0.2M

2022-2023 Precision-medicine platform trials to improve the care of sick and preterm newborn babies. Professor Victoria Cornelius and Professor Neena Modi. NIHR EME Accelerator Award. £0.19M

2022-2024 Development and feasibility testing of an intervention to prevent potentially harmful skincare practices during infancy (Babybathe). Dr Michael Perkin. NIHR RfPB. £0.2M

2021-2024 Dyslipidaemia Acute Coronary Syndromes (ACS) Decision Support System Implementation study (ZODIAC). Professor Kosh Ray. Sanofi-Aventis. £6M

2021-2022 Recording HArms in Behavioural change Intervention Trials (RHABIT). Professor Cindy Cooper. CTU Support. £0.07M

2021-2023 Long term effectiveness and cost-effectiveness of early mental health intervention: Follow up to the Healthy Start, Happy Start study. Professor Paul Ramchandani. NIHR HTA. £0.4M

2021-2023 A single-blind, randomised, phase II UK multi-centre study to determine reactogenicity and immunogenicity of booster vaccination against ancestral and novel variants of SARS-CoV-2 (COV-BOOST). Professor Saul Faust. NIHR/VTF, DHSC. £19M

2021-2024 A multi-site RCT to explore the clinical and cost effectiveness of the Circle of Security Intervention for mothers in perinatal mental health services (The COSI study). Professor Peter Fonegy. NIHR HTA. £2M

2021-2025 Sepsis Trials In Critical Care (SepTIC). Professor Anthony Gordon. NIHR HTA. £3M

2020-2022 Optimisation for blood Pressure with Single-Pill combinations in India (TOPSPIN). Professor Neil Poulter. Servier Pharmaceuticals. £0.3M

2020-2021 Multi-arm trial of Inflammatory Signal Inhibitors for COVID-19 (MATIS). Dr Nicola Cooper. Novartis and Rigel. £0.6M

2020-2026 Treating severe paediatric asthma; an open label randomised controlled trial comparing mepolizumab and omalizumab (TREAT trial). Professor Sejal Saglani. NIHR EME. £2M

2019-2021 Evaluating the use of apps for the management of chronic conditions in asthma. COPD, heart disease and diabetes. Dr Victoria Cornelius. Mymhealth commercial. £0.16M

2018-2020 Skin care interventions for preventing eczema and food allergy: a systematic review and individual participant data meta-analysis (Sci-PAD). Dr Robert Boyle. NIHR RfPB. £0.13M

2018-2020. Developing a Community Singing-Based Intervention for Perinatal Mental Health in The Gambia. Professor Lauren Steward. AHRC-MRC. £0.15M

2017-2018. Feasibility study to evaluate the integration of routinely collected mobile app and NHS trust data. Dr Victoria Cornelius. NIHR CTU Support Funding. £10K

2017-2020. The Grown Up Peanut Immunotherapy (GUPI) study: a single arm phase II efficacy study of oral immunotherapy (OIT) in adults with peanut allergy. Dr Steven Till. NIHR RfPB. £0.2M

2016-2023 The renoprotective effects of Ursodeoxycholic acid in patients with type 1 diabetes and macroalbuminuria. Dr Janaka Karalliedde. NIHR. £0.2M

2016-2020 Treatment of Pustular Psoriasis with the IL-1 receptor antagonist anakinra: a randomised, placebo controlled trial and associated mechanistic studies (APRICOT). Professor Catherine Smith. NIHR EME. £1.2M

2015-2017 A study to assess the feasibility and patient acceptability for an adapted diagnostic accuracy study to compare virtual vs conventional chromoendoscopy for the detection of dysplasia in colitis (CONVINCE). Dr Bu'Hussain Hayee. NIHR RfPB.£0.2M

2015-2017 The role of apixaban, aspirin and enoxaparin as thromboprophylaxis in patients newly diagnosed with multiple myeloma - an open label randomised feasibility study(TiMM). Professor Roopen Arya. NIHR RfPB. £0.17M

2015-2018 A feasibility study to evaluate local heat preconditioning with respect to its effects on wound healing after reconstructive breast surgery in patients with breast cancer– a single blind randomised controlled trial (PREHEAT). Mr Jian Farhadi. NIHR RfPB. £0.2M

2014-2018  Randomised Controlled Trial of intraocular and periocular steroid (triamcinolone acetonide) in eyes undergoing vitreoretinal surgery for open globe trauma (ASCOT). Mr David Charteris. NIHR HTA. £1.2M

2014-2018  A randomised placebo-controlled study examining the role of anti-IgE in severe recalcitrant paediatric atopic Eczema (ADAPT). Dr Susan Chan. NIHR EME. £0.48M

2017-2019 NIHR Research Methods Training Fellowship. Dr Victoria Cornelius. NIHR TCC.

2014-2016  Enhanced Invitation Methods to Increase Uptake of NHS Health Checks; a Randomised Controlled Trial. Professor Martin Gulliford. NIHR HTA. £0.37M

FELLOWSHIP SUPERVISION

2023-2026. Developing causal machine learning methods for the detection of heterogeneous treatment effects in randomised controlled trials, with application to critical care trials. Ellie Van Vogt. NIHR Doctoral Fellowship. NIHR.

2021-2024. Improving the evaluation of mental health digital health interventions in randomised

controlled trials by understanding and incorporating user engagement. NIHR Doctoral fellowship. Jack Elkes. NIHR TCC

2020-2023. Accessible statistical methods to determine treatments effects that matter to patients. NIHR Advanced fellowship. Dr Suzie Cro. NIHR TCC

2020-2022. NIHR Pre-doctoral fellowship (Eleanor Van Vogt). NIHR TCC

2019-2020. Mr Giles Partington. NIHR Reserach Training Methods Fellowship.

2018-2021. Improving the monitoring and analysis of harm outcomes in phase II and III pharmacology trials to facilitate early detection of adverse drug reactions (ADRs). Ms Rachel Phillips. NIHR Doctoral Fellowship.

2018 - 2020. Ms Anca Chis Ster. NIHR Reserach Training Methods Fellowship.

2018 - 2020. Dr Maeve Kelleher. NIHR Translational Fellowship.

2016 – 2021. EFFIP (E-support for Families and Friends of Individuals affected byPsychosis): A randomised controlled trial of a co-produced online intervention for carers. Dr Jacqueline Sin. NIHR Postdoctoral Fellowship.

2015 – 2020. Development and testing of predictive risk stratification models for anxiety and psychological distress at one-year post-chemotherapy in women with breast cancer. Ms Jenny Harris.

2014 – 2017. Understanding why girls from Black and minority ethnic backgrounds are less likely to receive the HPV vaccine: developing and testing a complex psychological intervention to increase uptake. Dr Alice Forster. CRUK Postdoctoral Fellowship.

2014 – 2017. Cognitive Orientation to Occupational Performance Intervention with Paediatric Dystonic Movement Disorders. Ms Hortensia Gimeno. NIHR Doctoral Fellowship

CURRENT OVERSIGHT COMMITTEE MEMBERSHIP

• DMC Chair: NIHR HTA: the BaCPAKS trial. Nerve Block for Chronic Pain After Knee replacement Surgery: A multi-centre, randomised, sham-controlled trial to investigate the clinical and cost effectiveness of adding an adductor canal block to standard perioperative approaches in primary elective knee joint replacement (Dr Ciro Morgese, University Hospitals Birmingham NHS Foundation Trust) 
• TSC Chair: NIHR: Community Health Intervention through Musical Engagement (CHIME) (Prof Lauren Stewart, University of Roehampton ProfSarah Skeen, Stellenbosch University)
• DMEC Chair: NIHR HTA: BAY Project. Behavioural Activation for Young people with depression in specialist child and adolescent mental health services. (Prof Bernadka Dubicka, The University of Manchester)
• DMEC Chair: Preventing food allergy in infants with early tastes of common food allergens: feasibility and cluster randomised controlled trial.NIHR PGfAR (Prof Graham Roberts, Southampton Clinical Trials Unit).
• DMEC Chair: In-BOAT: A Randomised Controlled Trial (RCT) of a Diazepam Maintenance Intervention versus Standard Care of Tapering Diazepam to Reduce Dependent Street Benzodiazepine Use in Adults Receiving Opioid Agonist Treatment (OAT). Professor Catriona Matheson (Stirling University)  
• DMEC member: Generating new evidence to REduce major COMplications to iMprove the safety and efficacy of Extracorporeal membrane oxygenatioN (ECMO) in severe carDiac and respiratory failure (RECOMMEND Trial). (Prof Carol Hodgson, Monash University).
• DMEC Member: NIHR: A Phase 2 randomised, single blinded, placebo controlled, cross-over trial of a single dose of live attenuated influenza vaccine in 12–23-month-old children (FluSNIFF-toddler) (Prof Saul Faust, University of Southampton) 
• Advisory Committee Member: Development of Guidelines for Bayesian Statistical Analysis Plans for Trials.  (Anna Heath, Canadian Health Research).