ProfessorSejal Saglani

Professor of Paediatric Respiratory Medicine

National Heart & Lung Institute - Faculty of Medicine

RESEARCH

RESEARCH PROGRAMME
Management of Preschool Wheeze

Use of molecular profiling to determine optimal management for moderate to severe preschool wheeze - NIHR, Prinicipal Investigator
Granulocyte activation and functional interactions with the bronchial epithelium and asthma control in children - Asthma UK, Principal Investigator
Gene-environment interactions mediating preschool wheeze: the role of 17q21, farmyard microbes and innate cytokines - Asthma UK, Principal Investigator
Patterns of airway infection and inflammation distinguish pathophysiological phenotypes in preschool wheezers independently of symptom pattern - British Lung Foundation, Principal Investigator
Mechanisms mediating Paediatric Severe Asthma

Role of innate lymphoid cells in mediating severe asthma in children
Interactions between T helper cells and innate lymphoid cells in steroid resistance in paediatric severe therapy resistant asthma
Collaborations
Breathing Together Study - Wellcome Trust Strategic Award:

Pulmonary epithelial barrier and immunological functions at birth and in early life – key determinants of the development of asthma?, Principal Investigator at Imperial and Chelsea & Westminster Hospital

GRANTS

  • GRANT
    Investigating the impact of synthetic mRNA on epithelial function in airways disease (BRC Respiratory Shadow Award)
    Imperial College Healthcare NHS Trust: Research Capability Funding (RCF)2 Dec 2020 - 31 Mar 2021
    Imperial College Healthcare NHS Trust: Research Capability Funding (RCF): Investigating the impact of synthetic mRNA on epithelial function in airways disease (BRC Respiratory Shadow Award) (2020-2021)
  • INTERNAL SCHEME
    BRC Respiratory Theme Pilot Projects Budget
    Imperial College Healthcare NHS Trust- BRC Funding
    Imperial College Healthcare NHS Trust- BRC Funding: BRC Respiratory Theme Pilot Projects Budget (2023-2027)