ProfessorRamon Vilar Compte

Head of Department, Prof of Medicinal Inorganic Chemistry

Department of Chemistry - Faculty of Natural Sciences

RESEARCH

The Vilar Group is a very multidisciplinary team of students and postdoctoral associates interested in developing new molecular tools to study biological systems. To this aim, we are active in several broad research areas including synthetic (organic and inorganic) chemistry, spectroscopic and biophysical characterisation, chemical biology and molecular recognition. Some of the areas of particular interest in the group are:

 

  • Chemical biology of nucleic acids with particular interest in G-quadruplex DNA
  • Development of optical probes to study cellular processes (e.g. probes selective to image nucleic acids, metal ions, cellular organelles).
  • Synthesis of metal-containing drugs and study of their interactions with DNA (as potential anticancer and antibacterial drugs) and proteins (as inhibitors of enzymes or to prevent pathological aggregation of peptides).
  • Understanding the cellular/biological functions of metal ions (e.g. copper and zinc).
  • Development of receptors for selective recognition of anions (phosphate, chloride, arsenate) and cations (mercury, lead) for the development of chemical sensors and materials to remove pollutants from contaminated water

 

For more details of research in the Vilar Group, please visit our website

GRANTS

  • STANDARD - RESPONSE
    An Accumulation Rulebook & Vulnerability Atlas for Klebsiella spp.
    Wellcome Trust22 Mar 2026 - 21 Mar 2029
    Wellcome Trust: An Accumulation Rulebook & Vulnerability Atlas for Klebsiella spp. (2026-2029)
  • STANDARD - CALL
    GSK-Fleming Initiative, Grand Challenge 2
    Glaxosmithkline Research and Development Ltd11 Nov 2025 - 10 Nov 2028
    Glaxosmithkline Research and Development Ltd: GSK-Fleming Initiative, Grand Challenge 2 (2025-2028)
  • STANDARD - CALL
    Research Cluster in Health Sciences, with the University of Hong Kong - Phase 2 LSCCB InnoHK
    HKCHE1 May 2025 - 30 Apr 2030
    HKCHE: Research Cluster in Health Sciences, with the University of Hong Kong - Phase 2 LSCCB InnoHK (2025-2030)
  • GRANT
    Photoactivatable molecular probes to study RNA-protein interactions - ICB CDT Co Funded studentship
    Vertex Pharmaceuticals (Europe) Ltd1 Oct 2022 - 30 Sep 2026
    Vertex Pharmaceuticals (Europe) Ltd: Photoactivatable molecular probes to study RNA-protein interactions - ICB CDT Co Funded studentship (2022-2026)
  • GRANT
    LABORATORY FOR SYNTHETIC CHEMISTRY AND CHEMICAL BIOLOGY LIMITED
    HKCHE Laboratory for Synthetic Chemistry and Chemical Biology Limited1 Aug 2020 - 30 Apr 2025
    HKCHE Laboratory for Synthetic Chemistry and Chemical Biology Limited: LABORATORY FOR SYNTHETIC CHEMISTRY AND CHEMICAL BIOLOGY LIMITED (2020-2025)