DrRachael Barry

Rachael's research focuses on hydrolytic enzymes (hydrolases) that are active in an inflamed and cancerous gut. Her team integrates approaches from chemistry (activity-based probes, proteomics), cell biology (e.g., organoids), engineering (e.g. gut-on-chip) and medical research (animal models of colon inflammation, patient samples). Our goal is to understand the role of hydrolases in driving colonic diseases and to uncover their potential as biomarkers and targets for chemoprevention and treatment.