ProfessorPaul Freemont

Chair in Protein Crystallography

Department of Infectious Disease - Faculty of Medicine

  • Chair in Protein Crystallography
    Department of Infectious Disease - Faculty of Medicine
  • 020 7594 5327 (Work)
  • 259, Sir Alexander Fleming Building, South Kensington Campus, United Kingdom

BIO

Professor Paul Freemont is Head of the Section of Structural and Synthetic Biology in the Department of Infectious Disease at Imperial College. The Section is based in South Kensington Sir Alexander Fleming Building and focuses on the molecular mechanisms of human disease and infection using the tools of integrated structural biology. In addition the Section also has research programs in synthetic biology focused on automation, cell free systems, microbiome engineering and printing. Please go to the Structural and Synthetic Biology Section website for news, up-to-date research summaries, a list of job opportunities, and information on lab members.

Professor Freemont is the co-founder of the Imperial College Centre for Synthetic Biology and Innovation and co-founder and co-director of the National UK Innovation and Knowledge Centre for Synthetic Biology (SynbiCITE - since 2013). He is also director of the London BioFoundry (since 2016). His research interests are focused on developing synthetic biology foundational tools, automation and biofoundries and cell-free systems for specific applications including biosensing, metabolic and protein engineering and synthetic cells. He is author of over 300 scientific publications and is an elected member of European Molecular Biology Organisation and Fellow of the Royal Society of Biology, Royal Society of Chemistry and Royal Society of Medicine and is an Honorary Fellow of the Royal College of Art. He also co-chairs the newly formed UK governments Engineering Biology Steering Group and is also a member of the Biosecurity Leadership Council. Internationally, he is currently a council member of the US Engineering Biology Research Consortium and chairs of the EBRC Policy and International Engagement Working Group. He is a member of the World Economic Forum Global Future Council on Synthetic Biology and is currently leading a US-funded Task Force on Engineering Biology Metrics and Technical Standards for Global Bioeconomy. He also co-founded and was founding chair of the Global Biofoundry Alliance, an organisation comprising 36 institutions worldwide that have established public-funded biofoundries for synthetic/engineering biology. He is a passionate advocate for the commercialisation of engineering biology and is co-founder of the Imperial spin-out Solena Materials and also SynBioVen, an early-stage seed investment company for engineering biology start-ups in the UK.

ACADEMIC POSITIONS

  • Professor and Head of Section of Structural and Synthetic Biology
    Imperial College London, Infectious Disease, London, United KingdomJun 2019 - present
  • Professor and Head of Section of Structural Biology
    Imperial College London, Medicine, London, United KingdomJun 2014 - Jun 2019
  • Co-Director UK National Innovation and Knowledge Centre for Synthetic Biology
    Imperial College London, United KingdomMay 2013 - present
  • Director of London Biofoundry
    Imperial College London, United KingdomNov 2019 - present
  • Head of Division
    Imperial College London, Molecular Biosciences, United KingdomJan 2005 - Dec 2012
  • Head of Centre for Structural Biology
    Imperial College London, London, United KingdomJan 2000 - Jan 2005
  • Principal Scientist
    Imperial Cancer Research Fund (now known as the Crick), London, United KingdomJan 1994 - Dec 1999
  • Research Scientist
    Imperial Cancer Research Fund (now known as the Crick), London, United KingdomJan 1989 - Jan 1994
  • Postdoctoral Fellow (Mike Crumpton Lab)
    Imperial Cancer Research Fund (now known as the Crick),, London, United KingdomDec 1987 - Dec 1989
  • Postodctoral Fellow (Tom Steitz Lab)
    Yale University, Molecular Biophysics and Biochemistry, New Haven, United StatesJan 1984 - Dec 1987

DEGREES

  • PhD
    University of Aberdeen, Aberdeen, United KingdomOct 1980 - Jan 1984
  • BSc Hons
    Heriot-Watt University, Edinburgh, United KingdomOct 1977 - Jun 1980

FACULTY

  • Faculty of Medicine

POSITION NAME

  • Chair in Protein Crystallography

FIELDS OF RESEARCH