ProfessorNicholas Grassly

Nicholas Grassly is a Professor in the Department of Infectious Disease Epidemiology and head of the Vaccine Epidemiology Research Group. He works on vaccine trials and disease surveillance. His research brings together epidemiological analysis and laboratory testing to identify optimal methods for disease prevention, focusing on pathogens in low- and middle-income countries such as polio, rotavirus, typhoid and emerging viruses. He works with a network of collaborators at institutes worldwide, including in the UK, Cambodia, DRC, France, Ghana, India, Indonesia, Malaysia, Mozambique, Nigeria, Pakistan, Senegal, Singapore, USA, and Zambia. 

He studied biology at Oxford University and trained in epidemiology at Imperial College London. He serves on various boards and committees, including the UK Joint Committee on Vaccination and Immunisation (JCVI). He teaches on the MSc (Epidemiology), MPH and undergraduate biomedical courses at Imperial College London. His work is funded by the MRC, Wellcome Trust, WHO and Gates Foundation.

Current research topics: Wastewater surveillance for Pandemic Prevention (WaSPP); Rapid diagnostics for poliovirus surveillance (DDNS); Epidemiology of polio eradication and endgame strategy; Environmental (wastewater) surveillance for Salmonella Typhi; Vaccine clinical trial design and analysis; Causes of oral vaccine failure (rotavirus and poliovirus); Human infection challenge for vaccine development; Vaccine-induced immune correlates of protection.