BIO

Marc-Emmanuel Dumas holds Imperial's Chair in Systems Medicine and is Head of the Division of Systems Medicine in the Department of Metabolism, Digestion and Reproduction. He is director of Imperial's Microbiome Network, a cross-faculty multidisciplinary network of excellence, made of >60 PIs and their groups to provide a unique focal point for research, teaching and public engagement activities around the microbiome at Imperial. He is a CNRS Director of Research and group leader at U1283/UMR8199 at the European Genomic Institute for Diabetes in Lille, France and leads the Imperial-University of Lille-CNRS International Research Project in Integrative Metabolism which was launched in 2023. He also holds an Adjunct Professorship at McGill University's Genome Innovation Centre and Department of Human Genetics in Montréal, Canada.

His research focusses on the metabolome in cardiometabolic diseases to better understand the key challenges in the integrative control of metabolism, blending genomics and microbiomics in systems medicine. His main research interest focusses on the role of the microbiome and its metabolic output (but is not limited to) in metabolic and cardiorespiratory diseases as well as in chronic inflammation, including neuroinflammation, and certain types of cancers. His group focusses on integrative metabolism, using metabolomics to identify novel markers and dissect their mechanisms in metabolic and cardiorespiratory conditions, and chronic inflammation, including neuroinflammation.

Current group members:

Research Fellows and Postdocs:
Dr. Kanta Chechi (MRC Research Fellow, ISSF Springboard Fellow, BRC Fellow) 

Dr. Elliot Murphy (Leverhulme postdoc on the holometabolome)

Dr. Antonis Myridakis

PhD students:

Ms Manyi Jia (PhD in multi-omics of cardiometabolic diseases) 
Mr Desai Chen (PhD COVID-19 metabolomics)
Ms Amelia (Yuan) Wang (PhD in microbiomics)
Ms Ema Mocsonokyova (PhD student in chemoinformatics, with Prof. Robert Glen, primary supervisor)
Ms Georgia Lorentzen (PhD student in mass spectrometry imaging, with Dr. Zoe Hall, primary supervisor)

Positions (currently 4 vacancies):
Excellent postdoctoral and PhD candidates with the following profiles are encouraged to get in touch:
- Analytical chemistry for development of untargeted and targeted metabolomic strategies by UPLC-HRMS in biomedical and environmental samples, ie holometabolome
- Computational metabolomics of the holobiont-derived metabolome (ie holometabolome) by UPLC-HRMS, ie metabolite annotation, dereplication, molecular networking and development of novel metrics reporting chemical information
- Analytical chemistry for the development of untargeted and targeted UPLC-MS methods for tracking endogenous and drug metabolism
- Computational metagenomics with a strong focus on metagenome and metabolome integration or mining
- Toxicologist/pharmacologist to characterise novel bioactivities for microbiome-derived compounds

Alumni:

Dr. Petros Andrikopoulos

Dr Angelos Manolias

Dr Nadeen Habboub

Dr. Gibril Ndow
Dr. Sachin Dubey

 

 

 

Ms Danae Zonias
Mr Khawaja Mustafa Shah
Ms Tamara Vujic
Ms Huilin Zhan 
Ms Tongxin Zhang 
Dr Hwei Ee Tan 
Dr. Flavia Valeo 
Dr. Michael Olanipekun 
Dr Haoran Peng 
Ms Wendy Peng 
Ms Anthonia Osagie 
Mr Xianyu (Adam) Zhu)
Ms Zoe Hoare
Prof. Alexandre Nuzzo
Mr. Ricardo Minaya Sainz
Mr. Linghen He
Dr. Francesco Pallotti
Ms Tatiana Mattio
Dr. Laura Martinez-Gili
Dr Julien Chilloux
Assoc. Prof. Ana Luisa Neves, MD PhD
Dr Andrea Rodriguez Martinez
Ms Ruby Kozlowski
Ms Elina Alambriti
Dr Magali Sarafian
Ms Leonie Kohlhammer
Mr Erik Marzaganov
Ms Valeria Nikolaenko
Ms Hajrah Sarkar
Ms Sophie Thayanithy
Ms Islay Campbell
Dr Mohd Badrin Hanizam Abdul-Rahim
Dr Abellona (Mei) U
Dr Jessica Le Ven 
Mr Aamer Mughal
Ms Sharim Ponticelli-Turner
Mr Michele Calabrese
Ms Emily (Zhanxuan) Wu
Prof. Lesley Hoyles
Ms Clare O'Malley
Mr Richard Perryman
Dr. Claire L. Boulangé
Dr Quan Gu
Ms Katarzyna Roguska
Dr Chi (Janice) Kwok
Ms Elisa Noll
Ms Jaya Venkitachalam
Ms Chloé Deshayes 
Ms Océane Carle
Dr Kyrillos Georgiadis Adesina
Dr Clément Pontoizeau
Dr Mohamed Triba
Dr Vincent Navratil
Dr Céline Domange
Dr Benjamin Blaise
Dr Laetitia Shintu

LANGUAGES

  • French
    Can read, write, speak, understand and peer review
  • English
    Can read, write, speak, understand and peer review

FACULTY

  • Faculty of Medicine

POSITION NAME

  • Chair in Systems Medicine

FIELDS OF RESEARCH