ProfessorLesley Hoyles

Metagenomics (microbiome and virome)

Transcriptomics (prokaryote and eukaryote)

Integration of computational and classical biology to better understand diversity and functionality of the gut microbiome (in vitro and in vivo)

Effect of gut-derived microbial metabolites on host health

Coriobacteriia associated with the gut microbiota

Klebsiella oxytoca complex and its bacteriophages

Biography
Professor Hoyles focuses on microbiome research. She combines microbiology and bioinformatics approaches in vitro and in vivo to understand how members of the gut microbiota function and influence human health and disease. She has specific expertise in anaerobic microbiology, and the processing and analyses of various types of omics data (microbiomic, transcriptomic, metabolomic, genomic). Using integrated systems-level approaches, Professor Hoyles has defined the contribution of the microbiome and its metabolites to non-alcoholic fatty liver disease, metabolic retroconversion and integrity of the blood–brain barrier. Professor Hoyles currently holds a full-time position at Nottingham Trent University, and holds an honorary position within the Department of Surgery & Cancer at Imperial College London.