DrLynne Sykes
Clinical Associate Professor in Obstetrics
Department of Metabolism, Digestion and Reproduction - Faculty of Medicine
- Clinical Associate Professor in ObstetricsDepartment of Metabolism, Digestion and Reproduction - Faculty of Medicine
- 020 7594 2186 (Work)
- 3007, Institute of Reproductive and Developmental Biology, Hammersmith Campus, United Kingdom
RESEARCH
Student supervision:
BSc
2015 Boyce,E. The effects of therapeutic concentrations of Sulfasalazine in amniocytes and Proinflammatory Genes in Human Amnion Epithelial Cells
2017 Anucha,E. The potential role of viral priming in the placenta in bacterial induced preterm labour
2018 Thurairajah, S. Peripheral blood neutrophil function in women at high risk of preterm labour (BSc in Immunology)
2019 Budwig, L. Leukocytes as predictive markers of histological chorioamnionitis in women with preterm prelabour rupture of fetal membranes
2020 Hyde, A. Maternal ABO phenotype and the risk of preterm birth
2022 Pasint-Magyar, J. Maternal ABO phenotype and the risk of preterm birth in a large population study
2022 Green, A. Maternal ABO phenotype and the risk of PPROM in a large population study
2023 Soubelet, O. Optimisation of immune phenotyping for the BUMP feasibility study
2023 Dos Santos, M. Long term Treatment outcomes for Large uterine Fibroids
2023 McCutcheon M. Endometrial receptivity of Uterine Anomalies
2024 Karas, K. Rate of complications following emergency cervical cerclage at Imperial College Healthcare NHS Trust
2024 Body, L. Vaginal microbiota opsonisation status in pregnant women treated with a live biotherapeutic
2024 Suresh, N. Exploring disparities in ethnicity and preterm birth and its influence on recruitment into preterm birth prevention studies
2024 Naseem, A. Endometrial receptivity of uterine anomalies
2025 Tan, J. Ultrasound indicated cervical cerclage: Exploring complications, pregnancy outcomes, vaginal microbial composition and immune response.
2025 Chan, E. Impact of maternal vaginal microbiome composition on pregnancy and neonatal outcomes in preterm birth
2026 Harris, T. History indicated cervical cerclage: Exploring rates of complications and efficacy in reduction of spontaneous preterm birth
2026 Brown, C. Associations between the gut microbiome and pregnancy outcomes
2026 Tie-Gill, A. Cervical length surveillance and the risk of spontaneous preterm birth in women who have a multi-fetal pregnancy
2026 Sina-Tanda, M. The risk of iatrogenic preterm birth in women who have a multi-fetal pregnancy.
MSc
2010 Hunte, E. The role of CRTH2 in murine myometrial contractility
2011 Yap, XJ. Chemoattractant Receptor Homologous to the T helper 2 cell (CRTH2) expression and function in T helper cells in pregnancy
2013 Thomson, K. Investigation of Sulfasalazine Treatment in the Prevention of Preterm Labour – Effect on NF-κB Activity
2014 Begum, Z. The anti-inflammatory effects of 15dPGJ2 in human cultured amniocytes
2017 Rai, R. The role of TLR3 in viral priming of myocytes
2017 Bura, S. Recognition of the vaginal microbiome by the maternal immune response in pregnancy.
2018 Ahmed, S. The vaginal microbiota and the local and systemic immune response in term and preterm deliveries
2018 San Martin, C. The role of TLR3 in viral priming of PBMCs
2018 Alqurashi, M. Normal and low density granulocytes in pregnancy, Labour and women at high risk of preterm labour (MSc in Immunology)
2023 Sandhu, B. Investigation of the complement cascade in human amnion cells
2024 Stone, K. Immune signature for women at risk of preterm birth during the COVID-19 pandemic
2024 Oseitwum-Paris, D. Characterisation of peripheral and cervical neutrophil effector functions
2024 De Leon, B. Investigating immune signatures following preterm prelabour rupture of membranes
2025 Malik, Z. Characterisation of factors affecting bacterial opsonisation
2026 Butler, V. Anti-surface layer protein antibodies in women treated with a live biotherapeutic Lactobacillus crispatus (LACTIN-V).
2026 Moore, H. Infectious diseases in pregnancy: Epidemiology, Immunity and Screening in Northwest London
MD
2026 Tom Sewell Reproductive outcomes and endometrial receptivity before and after surgical correction of uterine septae in patients with recurrent miscarriage
PhD
2019 Begam,Z, The role of viral priming in bacterial induced preterm labour
2020 Chan,D, Microbial – Maternal Host Immune Interactions in Pregnancy Preterm labour
2022: Gimeno-Molina,B, The role of neutrophils in microbial driven preterm birth
2025: Mountain, K. Patient stratification and prediction of preterm labour in women with prior cervical treatment and women with a history of PTB
GRANTS
- PROGRAMME GRANTThe Imperial College March of Dimes European Prematurity Research Centre 2022-2023 (Year 5 of P76171, linked to WSCR_P76171)March of Dimes
- PROGRAMME GRANTThe Imperial College March of Dimes European Prematurity Research Centre 2023-2024March of Dimes