RESEARCH

Current group members:
Jessica Griffiths - UK DRI Cross centre post doc
Eleonore Schneegans - PhD student
Bshaier Allehyany - PhD student
Tatiana Georgiades - PhD student
Matilda Burridge - PhD student (second supervisor)
Xingjian Wang - PhD student (second supervisor)
Stanley Williams - Placement student



Previous group members:
Emmeleia Psyllaki
Samrah Siddiqi
Rutvi Patel
Sabino Mendez Pastor
Yuewen Wu
Sulin Liu
Wenqi Cho
Amelia Schricker
Leire Melgosa
James Johnson (industry supervisor)
Judith Piegsa (industry supervisor)
Adam Harris (industry supervisor)

Communications:
Imaging Mass Cytometry for Dementia Research (invited speaker) International Single Cell Neurobiology meeting, Barbados May 2023

Glial and neuronal mechanisms contributing to differential genetic risks in TREM2 R47H and R62H variants in Alzheimer’s Disease (oral communication) ADPD Gothenburg March2023

Imaging Mass Cytometry for Dementia Research (invited speaker) UK DRI Proteomics meeting, Dundee September 2022

Development of a multi-‘omics atlas project for Alzheimer’s Disease (invited speaker) Joint LKC – Imperial meeting, September 2021

Development of a multi-‘omics atlas project for Alzheimer’s Disease (invited speaker) Neurodegeneration Challenge Network (CZI science) Maps to Mechanisms, April 2021

Targeting the synapse in Alzheimer’s Disease (invited speaker) University of Tasmania, March 2021

Development of a multi-‘omics atlas project for Alzheimer’s Disease (invited speaker) International Parkinson’s Disease Genetic Consortium meeting, July 2020

Targeting the synapse in Alzheimer’s Disease (invited speaker) Compass Pathways, August 2020

Reverse translation in practice: Gaining more valuable information from animal models in neurodegenerative drug discovery (oral communication) Neurodegenerative Drug Discovery, Paris, May 2019

In vivo two-photon imaging of the effects of tauopathy and amyloidopathy on synapses (oral communication) Neuroplasticity, Neuroregeneration, and Brain Repair, NYAS, New York, June 2017

In vivo two-photon imaging of the effects of tauopathy and amyloidopathy on synapses (oral communication) AD/PD, Vienna, March 2017

The effect of pathogenic transgene suppression on synapse dynamics during tauopathy (oral communication) Society for Neuroscience, Chicago, October 2015

Two-photon imaging of synapse dynamics in the rTg4510 model (oral communication – invited speaker) Imperial College London, October 2014

Two-photon imaging of structural synaptic changes in a tauopathy model (rTg4510) (oral communication) Society for Neuroscience, New Orleans, October 2012

In vivo 2-photon imaging of axonal degeneration and synaptic turnover after laser-mediated micro lesions in the adult brain (oral communication and poster) British Neuroscience Association, Harrogate, April 2011

Migration and Integration of stem cells in the CNS (oral communication – invited speaker) Institute of Psychiatry, King’s College London, April 2010

Stem Cell Tracking in the CNS (oral communication – invited speaker) Max Planck Institute for Neurological Diseases, Cologne, Germany, February 2008

Cell Tracking in the CNS (oral communication – invited speaker) Life Sciences Department Seminar, Open University, October 2007

Implanted Bone Marrow-derived Stem Cells in a model of PD: A PET and MRI study (oral communication) Society for Molecular Imaging, Hawaii, September 2006 (Student Travel Stipend Award)

Long-term visualisation of stem cells in the CNS (oral communication) NMR Symposium, Cambridge, March 2006

Long-term visualisation of stem cells in the CNS (poster and oral communication) Hounsfield Memorial Lecture, Imperial College, London, February 2006, (Finalist)

Outreach
‘Understanding a TREMendous risk in Alzheimer’s Disease’ – Making It Brain UK DRI conference for high school students, 2023
Brain hat workshop – Great exhibition Road Festival, 2023
Featured in ElevatHer podcast to hightlight inspirational women in science, 2021
‘Sciversity’ – a TikTok social media campaign to highlight positive diverse science role models to lower-income secondary school pupils, 2021
‘Academia vs Industry’ – UK DRI talk to early careers researchers, 2020
‘What is neuroscience?’ – a talk to primary school children about the brain, 2020
‘Crossing over to the dark side: from academia to industry’ - various careers talks at Imperial College, Institute of Cancer Research and British Pharmacological Society 2011-2019
Other activities
Teaching:
Lecturer on Biology Of Ageing module for BSc in Medical Biosciences course,
Lecturer on Cellular and Molecular Neuroscience module for MSc Translational Neuroscience,
King’s College Guest lecturer – ‘Discovery research in Industry’ on the Pharmaceutical Medicine program,
UCL Guest Lecturer – ‘Use of preclinical models in drug discovery’ on MSc Advanced biomedical Imaging course
Manuscript peer review: Cellular and Molecular Life Sciences, Molecular Neurodegeneration, Frontiers in Cellular Neuroscience, Neurobiology of Ageing, Alzheimer's Research & Therapy
Funding peer review: Alzheimer’s Society, Neurological Foundation of New Zealand
Guest editor: Fundamentals of 21st century Neuroscience in Frontiers in Molecular Neuroscience
Session Chair: British Neuroscience Association annual meeting (2021), UK DRI annual meeting (Connectome, 2021)
Professional memberships: Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment (ISTAART), Society for Neuroscience, British Neuroscience Association, International Society for Stem Cell Research
Human Tissue Act person designate for the Faculty of Medicine at White City campus
2014 Lilly Innovator Award ‘For introducing a new innovative microscopy method to study the mechanisms of neurodegeneration in an Alzheimer’s disease mouse model’

GRANTS

  • GRANT
    Proteomic changes at the synapse specific to Parkinson's disease dementia
    Alzheimer's Research UK (ARUK)1 Oct 2024 - 30 Sep 2027
    Alzheimer's Research UK (ARUK): Proteomic changes at the synapse specific to Parkinson's disease dementia (2024-2027)
  • GRANT
    Alzheimer's Research UK Imperial College London Network Centre 2020
    Alzheimer's Research UK (ARUK)1 Sep 2020 - 30 Apr 2022
    Alzheimer's Research UK (ARUK): Alzheimer's Research UK Imperial College London Network Centre 2020 (2020-2022)