DrJames Hindley

Dr James Hindley is Department Fellow in the Department of Chemistry at Imperial College London, the co-director of the Membrane Biophysics Group and part of the executive team of fabriCELL. His research focuses on the development of synthetic cells - biomimetic soft materials that aim to mimic the functions and behaviours of biological cells. Building cells from the bottom-up enables a better understanding of cell biology, as well as creating systems that can interface with biological systems. This second property makes synthetic cells a promising technology in applications across biomedicine.

Research topics of particular interest include:

Development of new signal transduction pathways that cannot be assembled in living systems
Engineering stimuli-responsive synthetic cells
Translation of synthetic cell technologies for biomedical application
High-throughput production/characterisation of synthetic cells
James is based in the EPSRC-funded Institute of Chemical Biology - Centre for Doctoral Training, and is associated with the Membrane Biophysics Platform and "CAPITALS" EPSRC Programme Grant.

RESEARCH HIGHLIGHTS

Designing new signalling pathways from the bottom-up in artificial cells - PNAS, Press Release

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Engineering light-responsive artificial cells that function as enzyme microreactors - Nature Communications, Press Release, Nature Research Blog - Science Imitates Art

Engineering patterned thermoresponsive vesicles for content release - Chemical Science