DrJose Antonio Aragon-Martin, PhD

He is the Research Director of Sonalee Laboratory, which is involved in Marfan syndrome and other related connective tissue genetic disorders like TAAD, EL, scoliosis, EDS, and so many others.

research projects - Sonalee Laboratory (not a complete list)
• Discovery of new drugs for Marfan syndrome using tissue from patients

• Discovery of new genes for TAAD (Thoracic Aortic Aneurysm and Dissection)

• Discovery of new genes for EL (Ectopia Lentis)

• Discovery of new genes for EDS (Ehler-Danlos syndrome)

• Discovery of new genes for scoliosis

• Genotype-Phenotype association in Marfan syndrome

• Animal models (zebrafish) for connective tissue disorders

• Moving from Sanger sequencing to NGS in Marfan syndrome genetic test

• CRISP-R technology to study connective tissue disorders

WE need help on
Bioinformatics

Statistics

STUDENTS
We can host:

Industrial Placement Students
Summer students
and other kind of volunteer students
that are seeking to gain laboratory skills in molecular genetics, and also skills in bioinformatics like variant interpretation and NGS (Next Generation Sequencing) analysis.

2020-2021 Academic MSc projects
* Variant confirmation and family segregation in EDS family 1

* Variant confirmation and family segregation in EDS family 2

* Study of known genes in an EDS family from NGS data

* Study of known genes in a TAAD family from NGS data

KEY LINKS
Marfan Trust Website:
* www.marfantrust.org

* www.marfantrust.org/about-us/the-sonalee-laboratory

* www.marfantrust.org/about-us/our-staff-and-trustees/director-of-sonalee-laboratory-dr-jose-antonio-aragon-martin,-bsc-(hons),-phd

Professional Websites:
* www.researchgate.net/profile/Jose_Aragon-Martin

* www.linkedin.com/in/jose-antonio-a-06a7a4ba/