ProfessorDavid Rueda
Chair in Molecular and Cellular Biophysics
Department of Infectious Disease - Faculty of Medicine
Orcid identifier0000-0002-0786-6726 (opens in a new tab)
- Chair in Molecular and Cellular BiophysicsDepartment of Infectious Disease - Faculty of Medicine
- +442083831604 (Work)
- 6.12D, LMS Building, Hammersmith Campus, United Kingdom
BIO
Professor, Imperial College London, 2012 - present
Associate Professor, Wayne State Univerisity, 2011 - 12
Assistant Professor, Wayne State Univerisity, 2005 - 11
Postdoctoral Fellow, University of Michigan, 2001 - 05
Doctor ès Sciences, EPF Lausanne, 2001
Dipl. Chem. Eng., EPF Lausanne, 1997
Our group develops and applies single-molecule imaging approaches to study how structural dynamics regulate fundamental biological processes involving proteins and nucleic acids across scales (from molecules to cells). We are particularly interested in elucidating various mechanistic aspects of DNA and RNA processing, such as chromatin structure and remodelling, DNA replication and repair, gene editing and RNA transcription, splicing and localization. Single-molecule microscopies reveal the structural dynamics of individual molecules, otherwise hidden in ensemble-averaged experiments. Thus, they enable us to observe reaction intermediates directly, even when short-lived or at low levels.
Team
Dr Paul Girvan - Postdoc
Dr Anita Meier - Postdoc
Dr Ben Ambrose - Postdoc
Dr Korak Ray - Postdoc
Dr Tianyi Zhang - Postdoc
Mr Quentin Smith - PhD Student
Mr Liu Fangqi - PhD Student
Mr Jan Vuckovick - PhD Student
Ms Deborah Egharevba - Technician
Mr Dionas Maroulis - Technician
Associate Professor, Wayne State Univerisity, 2011 - 12
Assistant Professor, Wayne State Univerisity, 2005 - 11
Postdoctoral Fellow, University of Michigan, 2001 - 05
Doctor ès Sciences, EPF Lausanne, 2001
Dipl. Chem. Eng., EPF Lausanne, 1997
Our group develops and applies single-molecule imaging approaches to study how structural dynamics regulate fundamental biological processes involving proteins and nucleic acids across scales (from molecules to cells). We are particularly interested in elucidating various mechanistic aspects of DNA and RNA processing, such as chromatin structure and remodelling, DNA replication and repair, gene editing and RNA transcription, splicing and localization. Single-molecule microscopies reveal the structural dynamics of individual molecules, otherwise hidden in ensemble-averaged experiments. Thus, they enable us to observe reaction intermediates directly, even when short-lived or at low levels.
Team
Dr Paul Girvan - Postdoc
Dr Anita Meier - Postdoc
Dr Ben Ambrose - Postdoc
Dr Korak Ray - Postdoc
Dr Tianyi Zhang - Postdoc
Mr Quentin Smith - PhD Student
Mr Liu Fangqi - PhD Student
Mr Jan Vuckovick - PhD Student
Ms Deborah Egharevba - Technician
Mr Dionas Maroulis - Technician
ACADEMIC POSITIONS
- ProfessorImperial College London, Department of Medicine, London, United Kingdom28 Sep 2012 - present
- Associate ProfessorWayne State University, Department of Chemistry, Detroit, United States15 Aug 2011 - 31 Aug 2012
- Assistant ProfessorWayne State University, Department of Chemistry, Detroit, United States15 Aug 2005 - 15 Aug 2011
DEGREES
- PhDEcole Polytechnique Federale de Lausanne, Lausanne, Switzerland1 Jul 1997 - 29 Jun 2001
- Dipl. Chem. Eng.Ecole Polytechnique Federale de Lausanne, Lausanne, Switzerland5 Oct 1992 - 18 Apr 1997
POSTGRADUATE TRAINING
- Postdoctoral FellowUniveristy of Michigan, Department of Chemistry, Ann Arbor, United States1 Aug 2001 - 15 Aug 2005BiophysicsPostdoctoral FellowshipSupervised by Nils G. Walter NGW
LANGUAGES
- EnglishCan read, write, speak, understand and peer review
- Spanish; CastilianCan read, write, speak, understand and peer review
- FrenchCan read, write, speak, understand and peer review
- GermanCan read, write, speak and understand
- ItalianCan read, write, speak and understand
FACULTY
- Faculty of Medicine
POSITION NAME
- Chair in Molecular and Cellular Biophysics