ProfessorDaryl Williams
Professor of Particle Science
Department of Chemical Engineering - Faculty of Engineering
Orcid identifier0000-0001-5626-5903 (opens in a new tab)
- Professor of Particle ScienceDepartment of Chemical Engineering - Faculty of Engineering
- 020 7594 5611 (Work)
- 439, ACE Extension, South Kensington Campus, United Kingdom
RESEARCH
Overview
Research interests
My current research interests focus on the particulate materials and material surfaces and their role in product manufacture including both biological and non-biological materials. I have developed a number of novel and leading edge methods for determining a range of surface and bulk physicochemical properties of powders and particulate materials including mechanical, topographical, chromatographic and surface properties.
Recent studies have included studies of protein aggregation, protein crystallisation and freeze drying. The group has world leading expertise in gravimetric charactisation methods as well as inverse chromatographic methods, having pioneered many of these approaches. For example, the water sorption characterisation of many classes of materials, especially pharmaceuticals, biomataterials and biopharmaceutical is an area of significant interest.
Current and new project areas include:
Biofilms and biocleaning of surfaces
Harvesting Water from Air with Surface Engineered Sponges
Aggregation behaviour of Crystallin –fundamentals of Cataract Formation
Inverse Liquid Chromatography for Reaction Engineering
A New Chromatographic Approach for Determining Protein Hydrophobicity and its relationship to Protein Aggregation and Unfolding
Fragrance and Malodour Molecule Sorption/Desorption into Solids
New Measurement Approaches for studying Caking behaviour of Powders
Surface Engineered Sponges: A Low-Cost Material for Bacteria Removal from Water
Removal of Volatile Organic Chemicals (VOC’s) from the Environment
Miniature Autonomous Sensors for Process Monitoring
Surface Acoustic Wave Sensors for remote temperature measurement •Advanced solids for CO2 sorption in carbon capture
Novel materials to inhibit biofilm adhesion for medical environments
Understanding Small Molecule Interactions with Hair
Stability of mABs therapeutics in solution
Formulation of peptide therapeutics
Selected research projects
Multi-Component Molecular Diffusion and Sorption in Complex Organic Solids using Inverse Gas Chromatography/Proton Transfer Reaction Mass Spectroscopy in collaboration with Brian Guthrie and Dave Butler download PDF
Micromechanical Properties of Microscopic Particles in collaboration with Brian Briscoe download PDF
Physicochemical Properties of Hydrates and Polymorphic Particulate Materials download PDF
Research interests
My current research interests focus on the particulate materials and material surfaces and their role in product manufacture including both biological and non-biological materials. I have developed a number of novel and leading edge methods for determining a range of surface and bulk physicochemical properties of powders and particulate materials including mechanical, topographical, chromatographic and surface properties.
Recent studies have included studies of protein aggregation, protein crystallisation and freeze drying. The group has world leading expertise in gravimetric charactisation methods as well as inverse chromatographic methods, having pioneered many of these approaches. For example, the water sorption characterisation of many classes of materials, especially pharmaceuticals, biomataterials and biopharmaceutical is an area of significant interest.
Current and new project areas include:
Biofilms and biocleaning of surfaces
Harvesting Water from Air with Surface Engineered Sponges
Aggregation behaviour of Crystallin –fundamentals of Cataract Formation
Inverse Liquid Chromatography for Reaction Engineering
A New Chromatographic Approach for Determining Protein Hydrophobicity and its relationship to Protein Aggregation and Unfolding
Fragrance and Malodour Molecule Sorption/Desorption into Solids
New Measurement Approaches for studying Caking behaviour of Powders
Surface Engineered Sponges: A Low-Cost Material for Bacteria Removal from Water
Removal of Volatile Organic Chemicals (VOC’s) from the Environment
Miniature Autonomous Sensors for Process Monitoring
Surface Acoustic Wave Sensors for remote temperature measurement •Advanced solids for CO2 sorption in carbon capture
Novel materials to inhibit biofilm adhesion for medical environments
Understanding Small Molecule Interactions with Hair
Stability of mABs therapeutics in solution
Formulation of peptide therapeutics
Selected research projects
Multi-Component Molecular Diffusion and Sorption in Complex Organic Solids using Inverse Gas Chromatography/Proton Transfer Reaction Mass Spectroscopy in collaboration with Brian Guthrie and Dave Butler download PDF
Micromechanical Properties of Microscopic Particles in collaboration with Brian Briscoe download PDF
Physicochemical Properties of Hydrates and Polymorphic Particulate Materials download PDF
GRANTS
- GRANTEPSRC Impact Acceleration Account 2017-2020Engineering & Physical Science Research Council (E1 Apr 2017 - 31 Mar 2022