ProfessorDanny O'Hare
Professor of Biosensor Technology
Department of Bioengineering - Faculty of Engineering
Orcid identifier0000-0002-0820-2999 (opens in a new tab)
- Professor of Biosensor TechnologyDepartment of Bioengineering - Faculty of Engineering
- 020 7594 5173 (Work)
- 4.07, Royal School of Mines, South Kensington Campus, United Kingdom
RESEARCH
Overview
Electrochemical sensors and biosensors for biomedical applications; lab-on-a-chip; signal processing; biofuel cells. Target analytes include: nitric oxide, dissolved oxygen, serotonin, dopamine, pH, tissue perfusion. For more information on the work of the Biosensor Group, please click here.
Current Projects
Cells on chips How do cells respond in the first few minutes after stimulation with a growth factor, drug or antigen? Are there characteristic signalling and metabolic responses? We have developed biocompatible arrays of microelectrode sensors to examine the effects of angiogenin and VEG-F on aortic endothelial cells and used similar approaches to look at bacterial antigens and macrophages
Microfabrication and microfluidics Sometimes it is advantageous to do bioanalysis off-line on a sample either from cells or living tissues. Such samples are typically tiny and new approaches to analytical methods are required. We've developed chromatographic techniques on a chip and combines this with droplet flow microfluidics to act as a tiny fraction collector.
Electrochemical sensors and biosensors for biomedical applications; lab-on-a-chip; signal processing; biofuel cells. Target analytes include: nitric oxide, dissolved oxygen, serotonin, dopamine, pH, tissue perfusion. For more information on the work of the Biosensor Group, please click here.
Current Projects
Cells on chips How do cells respond in the first few minutes after stimulation with a growth factor, drug or antigen? Are there characteristic signalling and metabolic responses? We have developed biocompatible arrays of microelectrode sensors to examine the effects of angiogenin and VEG-F on aortic endothelial cells and used similar approaches to look at bacterial antigens and macrophages
Microfabrication and microfluidics Sometimes it is advantageous to do bioanalysis off-line on a sample either from cells or living tissues. Such samples are typically tiny and new approaches to analytical methods are required. We've developed chromatographic techniques on a chip and combines this with droplet flow microfluidics to act as a tiny fraction collector.
GRANTS
- STANDARD - CALLImperial College Medical Technologies Overarching New Entreprise (MedTechONE)Wellcome Trust1 Jul 2022 - 30 Jun 2026
- STANDARD - CALLMRC UKRI IAA 22-25Medical Research Council (MRC)1 Apr 2022 - 31 Mar 2027